Abstract:
Grawa(v.amygdalina) and moringaoleifera were the most common traditional medicinal plants
used in Ethiopia. The parts of these plants such as stembark, leaves and flowers showed
varieties of medicinal properties and cure various human and animal diseases and ailments.
The phytochemical screening of the stem bark leaves and flower extracts were qualitatively
assessed using standard procedures in this study. Antibacterial activities of ethanol extracts of
stem bark, leaves andflower of v.amygdalina and moringaoleiferawere screened against ten
bacteria and one yeast these were carried out by the disc diffusion method on Mueller Hinton
agar (MHA). The crude ethanol extract of leaf of vernoniaamygdalina/grawa
showed13.50+0.75mm zone of inhibition on Candida albican, yeast and12.7+1.2mm zone of
inhibition on Listeria monocytogenes, positive bacteria and control drug Chloramphenicol
showed 12mm and 17mm zone of inhibition respectively. The ethanol extract showed
13.82+0.67mm zone of inhibition on Pseudomonas aeruginosa,gram,negative bacteria and
16.78+1.23mm zone of inhibition Enterococcus faecalis, gram positive bacteria and control
drug Chloramphenicol exhibited 16mm and20mm zone of inhibition respectively. Hence the
extracts were highly effective and consistent. The crude ethanol stem bark of
venoniaamygdalina extract was subjected to the antimicrobial activity and the results were
investigated. The crude extract showed 13.68+1.11 zone of inhibition on the Escherichia coli,
gram negative bacteria and 15.75+0.98 zone of inhibition on Staphylococcus epidermidis,
gram positive bacteria and the positive control Chloramphenicol showed 10mm and 10 mm
respectively. Thus the ethanol stem bark extract showed highly active and consistent on those
two bacteriaaginst Candida albican, Listeria monocytogene Pseudomonas aeruginosa and
Enterococcus faecalis bacteria.From two part of the plants, the vernoniaamygdalinathe ethanol
extract showed more bacterial activity than the other parts of moringa oleiferaagainst nine
bacteria(exceptSalmonella typhimurium) and one yeast, indicating that ethanol part
ofvernoniaamygdalinaextract have been variety of bioactive compounds.
